Molecule Details
| InChIKey | NRRBFJRUKPITFY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[6-[(3-Chlorophenyl)methoxy]-2-naphthyl]-1-(4-piperidylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine |
| Canonical SMILES | Nc1ncnc2c1c(-c1ccc3cc(OCc4cccc(Cl)c4)ccc3c1)nn2CC1CCNCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.06 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.4 | IC50 | ChEMBL;BindingDB |
| P00519 | ABL1 | Homo sapiens | Human | PF08919 PF07714 PF00017 PF00018 | 6.3 | IC50 | ChEMBL;BindingDB |
| A3FQ16 | Cryptosporidium parvum (strain Iowa II) | Pathogen | PF13499 PF00069 | 9.2 | IC50 | BindingDB | |
| Q6S4W0 | CDPK1 | Cryptosporidium parvum | Pathogen | PF13499 PF00069 | 9.2 | IC50 | BindingDB |
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 9.2 | IC50 | BindingDB |