Molecule Details
InChIKeyNQVIIUBWMBHLOZ-UHFFFAOYSA-N
Compound NameCvt-313
Canonical SMILESCOc1ccc(CNc2nc(N(CCO)CCO)nc3c2ncn3C(C)C)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.49
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
O76074 PDE5A Homo sapiens Human PF01590 PF00233 6.6 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.5 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
Q08499 PDE4D Homo sapiens Human PF18100 PF00233 6.4 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.4 IC50 ChEMBL;BindingDB
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.3 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 Clinical TTD_MultiTarget TTD_MultiTarget