Molecule Details
InChIKeyNQNSGMASKOVWNF-UHFFFAOYSA-N
Canonical SMILESNc1nc2cc(-c3ccc(F)c(C(=O)NCCC4(c5ccc(F)cc5)CC4)c3F)ccn2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.34
SourceBindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8NB16 MLKL Homo sapiens Human PF22215 PF07714 8.7 IC50 BindingDB
Q13546 RIPK1 Homo sapiens Human PF00531 PF07714 8.0 IC50 BindingDB