N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-methacryloylazetidine-2-carboxamide

InChIKey	`NQNCIKDFGVCZFY-UHFFFAOYSA-N`
Compound Name	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-methacryloylazetidine-2-carboxamide
Canonical SMILES	`C=C(C)C(=O)N1CCC1C(=O)Nc1cccc(CNc2nc(NC3CCOCC3)nc3c(C(C)C)cnn23)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.19
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P50613	CDK7	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL
P51946	CCNH	Homo sapiens	Human	PF16899 PF00134	6.2	IC50	ChEMBL;BindingDB
P51948	MNAT1	Homo sapiens	Human	PF25811 PF06391 PF17121	6.2	IC50	ChEMBL