Molecule Details
| InChIKey | NPQDLAMGUSTRMY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-Ethyl-3-(5-phenyl-1H-benzoimidazol-2-yl)-urea |
| Canonical SMILES | CCNC(=O)Nc1nc2cc(-c3ccccc3)ccc2[nH]1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.7 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00519 | ABL1 | Homo sapiens | Human | PF08919 PF07714 PF00017 PF00018 | 7.4 | IC50 | ChEMBL;BindingDB |
| P0AES4 | gyrA | Escherichia coli (strain K12) | Pathogen | PF03989 PF00521 | 6.4 | Ki | BindingDB |
| P0A0K8 | gyrB | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 6.3 | Ki | ChEMBL |