Molecule Details
InChIKeyNOOAKNBOIMAWSA-UHFFFAOYSA-N
Compound Name1-(4-chloro-3-fluorophenethyl)-4-(2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one
Canonical SMILESO=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1CCc1ccc(Cl)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL7.29
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P28482 MAPK1 Homo sapiens Human PF00069 9.0 Ki ChEMBL;BindingDB
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 7.0 Kd ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.0 Kd ChEMBL
P27361 MAPK3 Homo sapiens Human PF00069 6.2 IC50 ChEMBL