Molecule Details
InChIKeyNOMBUNHXDWBICV-DQSJHHFOSA-N
Canonical SMILESCN1CCN(CC(=O)N(C)c2ccc(N/C(=C3\C(=O)Nc4ccc(C(=O)O)cc43)c3ccccc3)cc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL8.1
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 8.7 IC50 ChEMBL;BindingDB
O43741 PRKAB2 Homo sapiens Human PF16561 PF04739 8.3 Ki ChEMBL
P54619 PRKAG1 Homo sapiens Human PF00571 8.3 Ki ChEMBL
P54646 PRKAA2 Homo sapiens Human PF16579 PF21147 PF00069 8.3 Ki ChEMBL;BindingDB
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 8.3 Ki ChEMBL
Q9UGI9 PRKAG3 Homo sapiens Human PF00571 8.3 Ki ChEMBL
Q9UGJ0 PRKAG2 Homo sapiens Human PF00571 8.3 Ki ChEMBL
Q9Y478 PRKAB1 Homo sapiens Human PF16561 PF04739 8.3 Ki ChEMBL
O60285 NUAK1 Homo sapiens Human PF00069 8.1 Ki ChEMBL;BindingDB
O14757 CHEK1 Homo sapiens Human PF00069 7.1 Ki ChEMBL;BindingDB
Q96RR4 CAMKK2 Homo sapiens Human PF00069 7.1 Ki ChEMBL;BindingDB