3-[3-tert-butyl-5-(naphthalen-1-ylcarbamoylamino)pyrazol-1-yl]-N-[2-(diethylamino)ethyl]benzamide

InChIKey	`NOBMKUVHFRVBES-UHFFFAOYSA-N`
Compound Name	3-[3-tert-butyl-5-(naphthalen-1-ylcarbamoylamino)pyrazol-1-yl]-N-[2-(diethylamino)ethyl]benzamide
Canonical SMILES	`CCN(CC)CCNC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	19
Pfam Stratification	Cross-Family
Avg pChEMBL	6.34
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q16539	MAPK14	Homo sapiens	Human	PF00069	7.1	Ki	ChEMBL
P16234	PDGFRA	Homo sapiens	Human	PF07679 PF25305 PF07714	6.6	Ki	ChEMBL
Q04759	PRKCQ	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.6	Ki	ChEMBL
P09619	PDGFRB	Homo sapiens	Human	PF00047 PF13927 PF25305 PF07714	6.5	Ki	ChEMBL
P17612	PRKACA	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	6.5	Ki	ChEMBL
O94806	PRKD3	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.4	Ki	ChEMBL
P51817	PRKX	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
O96013	PAK4	Homo sapiens	Human	PF00786 PF00069	6.3	Ki	ChEMBL
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.3	Ki	ChEMBL
Q16620	NTRK2	Homo sapiens	Human	PF07679 PF13855 PF16920 PF01462 PF07714	6.3	Ki	ChEMBL
Q9UM73	ALK	Homo sapiens	Human	PF12810 PF00629 PF07714	6.3	Ki	ChEMBL
P29376	LTK	Homo sapiens	Human	PF12810 PF07714	6.2	Ki	ChEMBL
Q9Y463	DYRK1B	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q06418	TYRO3	Homo sapiens	Human	PF00041 PF07679 PF07714	6.1	Ki	ChEMBL
P36507	MAP2K2	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
P49336	CDK8	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
Q16288	NTRK3	Homo sapiens	Human	PF07679 PF00047 PF13855 PF16920 PF01462 PF07714	6.0	Ki	ChEMBL