InChIKey	NNYBQONXHNTVIJ-UHFFFAOYSA-N
Canonical SMILES	CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.21
Source	ChEMBL;BindingDB

DrugBank ID	DB00749
Drug Name	Etodolac
CAS Number	41340-25-4
Groups	approved investigational vet_approved
ATC Codes	M01AB08
Description	Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.

---

Categories: Acetic Acid Derivatives and Related Substances Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents COX-2 Inhibitors Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Enzyme Inhibitors Heterocyclic Compounds, Fused-Ring Indoleacetic Acids Indoles Musculo-Skeletal System Nephrotoxic agents OAT1/SLC22A6 inhibitors Other Nonsteroidal Anti-inflammatory Agents Peripheral Nervous System Agents Photosensitizing Agents Selective Cyclooxygenase 2 Inhibitors (NSAIDs) Sensory System Agents UGT1A3 substrates UGT1A9 Substrates UGT2B7 substrates

---

Cross-references: BindingDB: 50016799 ChEBI: 4909 CHEMBL622 ChemSpider: 3192 Drugs Product Database (DPD): 1880 C06991 D00315 PharmGKB: PA449550 PubChem:3308 PubChem:46505184 RxCUI: 24605 Therapeutic Targets Database: DAP000778 Wikipedia: Etodolac