Molecule Details
| InChIKey | NNWNTVVLCCOLEQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione |
| Canonical SMILES | O=c1[nH]c2sccc2c(=O)n1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.11 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28715 | ERCC5 | Homo sapiens | Human | PF00867 PF00752 | 10.0 | IC50 | ChEMBL;BindingDB |
| P39748 | FEN1 | Homo sapiens | Human | PF00867 PF00752 | 9.3 | IC50 | ChEMBL;BindingDB |
| Q72547 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00075 PF00078 PF06815 PF06817 | 6.7 | IC50 | ChEMBL;BindingDB |
| P16732 | TRM3 | Human cytomegalovirus (strain AD169) | Pathogen | PF02499 PF02500 | 6.4 | IC50 | ChEMBL |