2-(2,6-dimethyl-4-pyridinyl)-3-propan-2-yl-5-[1-(1H-pyrazol-4-ylmethyl)piperidin-4-yl]-1H-indole

InChIKey	`NNHJMGVORBPPFP-UHFFFAOYSA-N`
Compound Name	2-(2,6-dimethyl-4-pyridinyl)-3-propan-2-yl-5-[1-(1H-pyrazol-4-ylmethyl)piperidin-4-yl]-1H-indole
Canonical SMILES	`Cc1cc(-c2[nH]c3ccc(C4CCN(Cc5cn[nH]c5)CC4)cc3c2C(C)C)cc(C)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.2
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9NYK1	TLR7	Homo sapiens	Human	PF13855 PF01582	8.9	IC50	ChEMBL;BindingDB
Q9NR97	TLR8	Homo sapiens	Human	PF13855 PF01582	8.5	IC50	ChEMBL;BindingDB
Q9NR96	TLR9	Homo sapiens	Human	PF18837 PF13516 PF13855 PF01582	7.2	IC50	ChEMBL;BindingDB