(8S,11R,12S)-11-[[4-(2,6-difluorophenyl)phenyl]methyl]-12-N-hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide

InChIKey	`NMVSNTFENGJBJY-XFAFFCHDSA-N`
Compound Name	(8S,11R,12S)-11-[[4-(2,6-difluorophenyl)phenyl]methyl]-12-N-hydroxy-8-N-(2-morpholin-4-yl-2-oxoethyl)-2,10-dioxo-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
Canonical SMILES	`O=C1NCCCC[C@@H](C(=O)NCC(=O)N2CCOCC2)NC(=O)[C@H](Cc2ccc(-c3c(F)cccc3F)cc2)[C@@H](C(=O)NO)CCCO1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.43
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	9.2	pIC50	TTD_MultiTarget
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	7.7	Ki	ChEMBL;BindingDB