Molecule Details
| InChIKey | NMVLJLKIUKOKSB-SANMLTNESA-N |
|---|---|
| Compound Name | 4-amino-3,5-dichloro-N-[(11R)-12-oxo-9-phenyl-6-pyrrolidin-1-yl-1,10-diazatricyclo[6.4.1.04,13]trideca-4(13),5,7,9-tetraen-11-yl]benzamide |
| Canonical SMILES | Nc1c(Cl)cc(C(=O)N[C@@H]2N=C(c3ccccc3)c3cc(N4CCCC4)cc4c3N(CC4)C2=O)cc1Cl |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.1 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.1 | IC50 | ChEMBL |