Molecule Details
| InChIKey | NMIHFSQPVACNNT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(1-methyl-1H-indol-5-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Canonical SMILES | Cn1ccc2cc(-c3nn(CC4CCNCC4)c4ncnc(N)c34)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.96 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 8.0 | IC50 | BindingDB |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.0 | IC50 | ChEMBL;BindingDB |
| A3FQ16 | Cryptosporidium parvum (strain Iowa II) | Pathogen | PF13499 PF00069 | 7.9 | IC50 | BindingDB |