Molecule Details
| InChIKey | NLZNSSWGRVBWIX-KRCBVYEFSA-N |
|---|---|
| Compound Name | Z-Wehd-fmk |
| Canonical SMILES | COC(=O)CC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.5 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q14790 | CASP8 | Homo sapiens | Human | PF01335 PF00656 | 6.7 | IC50 | ChEMBL |
| P55211 | CASP9 | Homo sapiens | Human | PF00619 PF00656 | 6.6 | IC50 | ChEMBL |
| P51878 | CASP5 | Homo sapiens | Human | PF00619 PF00656 | 6.5 | IC50 | ChEMBL |
| P55210 | CASP7 | Homo sapiens | Human | PF00656 | 6.2 | IC50 | ChEMBL |