Molecule Details
| InChIKey | NKOQGUAOVGXWMB-UHFFFAOYSA-N |
|---|---|
| Compound Name | [3-amino-2-(2-methyl-3H-benzimidazol-5-yl)-3,4-dihydropyrazol-4-yl]-[6-[[bis(2-methoxyethyl)amino]methyl]-1H-indol-2-yl]methanone |
| Canonical SMILES | COCCN(CCOC)Cc1ccc2cc(C(=O)C3C=NN(c4ccc5[nH]c(C)nc5c4)C3N)[nH]c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.71 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 8.0 | IC50 | ChEMBL;BindingDB |
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 7.6 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 7.5 | IC50 | ChEMBL;BindingDB |