Molecule Details
| InChIKey | NJETXHOGHMMTEB-KPKJPENVSA-N |
|---|---|
| Compound Name | (Z)-2-(6-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-pyridin-3-ylprop-2-enenitrile |
| Canonical SMILES | COc1ccc2c(/C(C#N)=C/c3cccnc3)c[nH]c2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.88 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.2 | IC50 | ChEMBL;BindingDB |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 7.0 | IC50 | ChEMBL;BindingDB |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.7 | IC50 | ChEMBL;BindingDB |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 6.6 | IC50 | ChEMBL;BindingDB |