Molecule Details
| InChIKey | NJEBVFDXJAFAGB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-{4-Amino-3-[2-(Cyclopropyloxy)quinolin-6-Yl]-1h-Pyrazolo[3,4-D]pyrimidin-1-Yl}-2-Methylpropan-2-Ol |
| Canonical SMILES | CC(C)(O)Cn1nc(-c2ccc3nc(OC4CC4)ccc3c2)c2c(N)ncnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.98 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O94806 | PRKD3 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 6.5 | IC50 | ChEMBL;BindingDB |
| A0A0F7UUA6 | Toxoplasma gondii (strain ATCC 50861 / VEG) | Pathogen | PF13499 PF00069 | 8.7 | IC50 | BindingDB | |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.7 | IC50 | ChEMBL;BindingDB |