Molecule Details
InChIKeyNIIYHUNRXQLMBG-UHFFFAOYSA-N
Compound Name5-[4-Amino-1-(oxolan-2-ylmethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine
Canonical SMILESNc1nc2cc(-c3nn(CC4CCCO4)c4ncnc(N)c34)ccc2o1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.3
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P42345 MTOR Homo sapiens Human PF02259 PF02260 PF08771 PF23593 PF11865 PF00454 8.3 IC50 ChEMBL
P42336 PIK3CA Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 7.4 IC50 ChEMBL
P78527 PRKDC Homo sapiens Human PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454 7.3 IC50 ChEMBL
P48736 PIK3CG Homo sapiens Human PF00454 PF00792 PF00794 PF00613 PF19710 7.1 IC50 ChEMBL
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 6.9 IC50 ChEMBL
O00329 PIK3CD Homo sapiens Human PF00454 PF00792 PF02192 PF00794 PF00613 6.8 IC50 ChEMBL