Molecule Details
InChIKeyNHXVGMQFCYBLTL-ZWNOBZJWSA-N
Compound NameGdc-0339
Canonical SMILESCn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CC[C@@H](N)[C@H](F)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.83
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 10.7 Ki ChEMBL;BindingDB
P11309 PIM1 Homo sapiens Human PF00069 10.5 Ki ChEMBL;BindingDB
Q9P1W9 PIM2 Homo sapiens Human PF00069 10.0 Ki ChEMBL;BindingDB
P14416 DRD2 Homo sapiens Human PF00001 6.3 IC50 ChEMBL
P21728 DRD1 Homo sapiens Human PF00001 6.3 IC50 ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 6.3 IC50 ChEMBL
P21918 DRD5 Homo sapiens Human PF00001 6.3 IC50 ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 6.3 IC50 ChEMBL;BindingDB