Molecule Details
| InChIKey | NGJLOFCOEOHFKQ-YVMONPNESA-N |
|---|---|
| Compound Name | SMI-4a |
| Canonical SMILES | O=C1NC(=O)/C(=C/c2cccc(C(F)(F)F)c2)S1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.81 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P11309 | PIM1 | Homo sapiens | Human | PF00069 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q9P1W9 | PIM2 | Homo sapiens | Human | PF00069 | 7.0 | IC50 | ChEMBL |
| Q9NZ45 | CISD1 | Homo sapiens | Human | PF10660 PF09360 | 6.5 | Ki | ChEMBL;BindingDB |
| P02766 | TTR | Homo sapiens | Human | PF00576 | 6.1 | IC50 | ChEMBL;BindingDB |