Molecule Details
| InChIKey | NGDXEOHYWJHBTJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[3-(4-fluorophenyl)-1-methylpyrazol-4-yl]-6-methyl-7H-pyrrolo[3,4-b]pyridin-5-one |
| Canonical SMILES | CN1Cc2nccc(-c3cn(C)nc3-c3ccc(F)cc3)c2C1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.75 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P48730 | CSNK1D | Homo sapiens | Human | PF00069 | 8.0 | IC50 | ChEMBL;BindingDB |
| P49674 | CSNK1E | Homo sapiens | Human | PF00069 | 7.4 | IC50 | ChEMBL |
| P48729 | CSNK1A1 | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL |
| Q16539 | MAPK14 | Homo sapiens | Human | PF00069 | 6.1 | IC50 | ChEMBL |
| O95819 | MAP4K4 | Homo sapiens | Human | PF00780 PF00069 | 6.1 | IC50 | ChEMBL |