Molecule Details
| InChIKey | NGDQZHZQUZQYHB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-Methyl-2-[9-propan-2-yl-6-(pyrimidin-5-ylamino)purin-2-yl]propan-1-ol |
| Canonical SMILES | CC(C)n1cnc2c(Nc3cncnc3)nc(C(C)(C)CO)nc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.9 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P20248 | CCNA2 | Homo sapiens | Human | PF02984 PF00134 PF16500 | 7.0 | IC50 | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 7.0 | IC50 | ChEMBL |
| P78396 | CCNA1 | Homo sapiens | Human | PF02984 PF00134 PF16500 | 7.0 | IC50 | ChEMBL |
| Q00535 | CDK5 | Homo sapiens | Human | PF00069 | 6.8 | IC50 | ChEMBL |
| Q15078 | CDK5R1 | Homo sapiens | Human | PF03261 | 6.7 | IC50 | ChEMBL;BindingDB |