Molecule Details
InChIKeyNGDNKYRUKIPCLK-UHFFFAOYSA-N
Compound NameN-benzyl-6-pyridin-4-yl-1,3-benzothiazol-2-amine
Canonical SMILESc1ccc(CNc2nc3ccc(-c4ccncc4)cc3s2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.85
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 8.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.8 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.7 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.0 Ki ChEMBL