Molecule Details
| InChIKey | NFVRGDRCCNEGBS-LGGPFLRQSA-N |
|---|---|
| Compound Name | L-817,818 |
| Canonical SMILES | C[C@H](N)COC(=O)[C@H](CCCCN)NC(=O)Cc1c(-c2ccc3ccccc3c2)[nH]c2c1ccc1ccccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.89 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35346 | SSTR5 | Homo sapiens | Human | PF00001 | 9.4 | IC50 | ChEMBL;BindingDB |
| P30872 | SSTR1 | Homo sapiens | Human | PF00001 | 8.5 | Ki | BindingDB |
| P30874 | SSTR2 | Homo sapiens | Human | PF00001 | 7.3 | Ki | BindingDB |
| P32745 | SSTR3 | Homo sapiens | Human | PF00001 | 7.2 | Ki | BindingDB |
| P31391 | SSTR4 | Homo sapiens | Human | PF00001 | 7.1 | Ki | BindingDB |