Molecule Details
InChIKeyNFSTZPMYAZRZPC-UHFFFAOYSA-N
Canonical SMILESO=[N+]([O-])c1cccc2c(Br)n[nH]c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.65
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB01997
Drug Name3-Bromo-7-Nitroindazole
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan
Categories: Heterocyclic Compounds, Fused-Ring Nitric Oxide Synthase, antagonists & inhibitors Pyrazoles
Cross-references: BindingDB: 50270528 CHEMBL479014 ChemSpider: 1587 PDB: INE PubChem:1649 PubChem:46507791 ZINC: ZINC000003870920
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P29475 NOS1 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 PF00595 6.8 IC50 ChEMBL;BindingDB
P35228 NOS2 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 6.5 IC50 ChEMBL;BindingDB
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P29474 NOS3 Nitric oxide synthase 3 inhibitor targets
P29475 NOS1 Nitric oxide synthase 1 inhibitor targets
P35228 NOS2 Nitric oxide synthase, inducible inhibitor targets