Molecule Details
InChIKeyNFHRQQKPEBFUJK-HSZRJFAPSA-N
Compound NameDevazepide
Canonical SMILESCN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)N=C(c2ccccc2)c2ccccc21
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.15
SourceBindingDB;ChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB20841
Drug NameDevazepide
CAS Number103420-77-5
Groups experimental
ATC Codes nan
DescriptionDevazepide is a small molecule drug. Devazepide has a monoisotopic molecular weight of 408.16 Da.

Categories: Benzazepines Benzodiazepines and benzodiazepine derivatives Benzodiazepinones Central Nervous System Depressants Heterocyclic Compounds, Fused-Ring Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists
Cross-references: BindingDB: 50005463 ChEBI: 4460 CHEMBL9506 C11710 PDB: 1OZ ZINC: ZINC000001847292
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P32238 CCKAR Homo sapiens Human PF00001 PF09193 9.7 IC50 ChEMBL;BindingDB
P32239 CCKBR Homo sapiens Human PF00001 6.6 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P32238 CCKAR Cholecystokinin receptor type A antagonist targets