(2-{N-[1-Carbamoyl-2-(1H-indol-3-yl)-ethyl]-hydrazinocarbonyl}-5-phenyl-pentyl)-{2-phenyl-1-[(quinoline-2-carbonyl)-amino]-ethyl}-phosphinic acid

InChIKey	`NFDNOGJHVSTSMJ-UHFFFAOYSA-N`
Compound Name	(2-{N-[1-Carbamoyl-2-(1H-indol-3-yl)-ethyl]-hydrazinocarbonyl}-5-phenyl-pentyl)-{2-phenyl-1-[(quinoline-2-carbonyl)-amino]-ethyl}-phosphinic acid
Canonical SMILES	`NC(=O)C(Cc1c[nH]c2ccccc12)N(N)C(=O)C(CCCc1ccccc1)CP(=O)(O)C(Cc1ccccc1)NC(=O)c1ccc2ccccc2n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Homologous
Avg pChEMBL	7.21
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	8.3	Ki	ChEMBL;BindingDB
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	7.9	Ki	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	7.7	pIC50	TTD_MultiTarget
P50281	MMP14	Homo sapiens	Human	PF11857 PF00045 PF00413 PF01471	7.2	Ki	ChEMBL;BindingDB
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	6.5	Ki	ChEMBL;BindingDB
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	6.5	pIC50	TTD_MultiTarget
P09237	MMP7	Homo sapiens	Human	PF00413 PF01471	6.4	Ki	ChEMBL;BindingDB