Molecule Details
InChIKeyNFBNIRNKYJTDIE-UHFFFAOYSA-N
Compound Name4-[4,4-bis(4-fluorophenyl)butyl]-N-[2-(4-ethoxyphenyl)ethyl]piperazine-1-carboxamide
Canonical SMILESCCOc1ccc(CCNC(=O)N2CCN(CCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.13
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P28223 HTR2A Homo sapiens Human PF00001 6.6 IC50 ChEMBL;BindingDB
P35462 DRD3 Homo sapiens Human PF00001 6.5 IC50 ChEMBL;BindingDB
Q99720 SIGMAR1 Homo sapiens Human PF04622 6.3 IC50 ChEMBL;BindingDB
P25021 HRH2 Homo sapiens Human PF00001 6.1 IC50 ChEMBL;BindingDB
P50406 HTR6 Homo sapiens Human PF00001 6.1 IC50 ChEMBL;BindingDB
P25103 TACR1 Homo sapiens Human PF00001 6.1 IC50 ChEMBL;BindingDB
O60840 CACNA1F Homo sapiens Human PF08763 PF16885 PF16905 PF00520 6.1 IC50 ChEMBL
Q01668 CACNA1D Homo sapiens Human PF08763 PF16885 PF16905 PF00520 6.1 IC50 ChEMBL
Q13698 CACNA1S Homo sapiens Human PF08763 PF16905 PF00520 6.1 IC50 ChEMBL
Q13936 CACNA1C Homo sapiens Human PF08763 PF16885 PF16905 PF00520 6.1 IC50 ChEMBL;BindingDB
P21728 DRD1 Homo sapiens Human PF00001 6.0 IC50 ChEMBL;BindingDB
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 6.0 pIC50 TTD_MultiTarget
P25100 ADRA1D Homo sapiens Human PF00001 6.0 IC50 ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.0 pIC50 TTD_MultiTarget
P35368 ADRA1B Homo sapiens Human PF00001 6.0 IC50 ChEMBL
Q01959 SLC6A3 Homo sapiens Human PF00209 6.0 IC50 ChEMBL;BindingDB