6-[[[1-[2-[3-Chloro-5-(2-hydroxyethyl)-6-oxo-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-3,4-dihydropyrido[3,2-b][1,4]oxazin-2-one

InChIKey	`NEUBWAWYTMZOPY-UHFFFAOYSA-N`
Compound Name	6-[[[1-[2-[3-Chloro-5-(2-hydroxyethyl)-6-oxo-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-3,4-dihydropyrido[3,2-b][1,4]oxazin-2-one
Canonical SMILES	`O=C1CNc2nc(CNC34CCC(CCc5c(Cl)cnc6ccc(=O)n(CCO)c56)(CC3)OC4)ccc2O1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.85
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P0AES4	gyrA	Escherichia coli (strain K12)	Pathogen	PF03989 PF00521	6.8	IC50	ChEMBL;BindingDB
P0AES6	gyrB	Escherichia coli (strain K12)	Pathogen	PF00204 PF00986 PF21249 PF18053 PF02518 PF01751	6.8	IC50	ChEMBL