Molecule Details
InChIKeyNERQMDXDVAZVNX-UHFFFAOYSA-N
Compound NameN-(furan-2-ylmethylideneamino)-6-(3-methyl-5-phenylpyrazol-1-yl)pyrimidin-4-amine
Canonical SMILESCc1cc(-c2ccccc2)n(-c2cc(NN=Cc3ccco3)ncn2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL6.48
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.5 Ki ChEMBL
P04626 ERBB2 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.4 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.1 Ki ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL