N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-[(5-methylthieno[2,3-d]pyrimidin-4-yl)amino]-1H-pyrazole-5-carboxamide

InChIKey	`NEQUYNFKQDRNGP-UHFFFAOYSA-N`
Compound Name	N-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-4-[(5-methylthieno[2,3-d]pyrimidin-4-yl)amino]-1H-pyrazole-5-carboxamide
Canonical SMILES	`Cc1csc2ncnc(Nc3c[nH]nc3C(=O)Nc3ccc(CN4CCN(C)CC4)cc3)c12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.83
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	9.8	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	8.3	IC50	ChEMBL;BindingDB
P78396	CCNA1	Homo sapiens	Human	PF02984 PF00134 PF16500	8.3	IC50	ChEMBL