Molecule Details
| InChIKey | NDDAHWYSQHTHNT-JTQLQIEISA-N |
|---|---|
| Compound Name | Indapamide, (S)- |
| Canonical SMILES | C[C@H]1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 12 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.13 |
| Source | BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB07467 |
|---|---|
| Drug Name | (S)-Indapamide |
| CAS Number | 77083-53-5 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: PDB: BL1 PubChem:12598931 PubChem:99443938 ZINC: ZINC000000601305
Target Activities (12)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9ULX7 | CA14 | Homo sapiens | Human | PF00194 | 8.3 | Kd | BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 8.0 | Kd | BindingDB |
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 7.7 | Kd | BindingDB |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 7.4 | Kd | BindingDB |
| Q9Y2D0 | CA5B | Homo sapiens | Human | PF00194 | 7.2 | Kd | BindingDB |
| P22748 | CA4 | Homo sapiens | Human | PF00194 | 7.1 | Kd | BindingDB |
| Q8N1Q1 | CA13 | Homo sapiens | Human | PF00194 | 7.0 | Kd | BindingDB |
| P07451 | CA3 | Homo sapiens | Human | PF00194 | 7.0 | Kd | BindingDB |
| P23280 | CA6 | Homo sapiens | Human | PF00194 | 6.6 | Kd | BindingDB |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 6.6 | Kd | BindingDB |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 6.5 | Kd | BindingDB |
| P35218 | CA5A | Homo sapiens | Human | PF00194 | 6.2 | Kd | BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P00918 | CA2 | Carbonic anhydrase 2 | binder | targets |