Molecule Details
| InChIKey | NCWNVZMHTRKEOP-MRXNPFEDSA-N |
|---|---|
| Compound Name | 3-(2,6-difluorophenyl)-7-[(5-fluoro-2-pyridinyl)amino]-1-[(3R)-1-methylpyrrolidin-3-yl]-1,6-naphthyridin-2-one |
| Canonical SMILES | CN1CC[C@@H](n2c(=O)c(-c3c(F)cccc3F)cc3cnc(Nc4ccc(F)cn4)cc32)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.26 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07948 | LYN | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.3 | IC50 | ChEMBL;BindingDB |
| P12931 | SRC | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.3 | IC50 | ChEMBL;BindingDB |
| Q06187 | BTK | Homo sapiens | Human | PF00779 PF00169 PF07714 PF00017 PF00018 | 6.3 | IC50 | ChEMBL;BindingDB |