Molecule Details
InChIKeyNBHPRWLFLUBAIE-UHFFFAOYSA-N
Compound NameHalopemide
Canonical SMILESO=C(NCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1ccc(F)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.45
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB20096
Drug NameHalopemide
CAS Number59831-65-1
Groups experimental
ATC Codes nan
DescriptionHalopemide is a small molecule drug. Halopemide has a monoisotopic molecular weight of 416.14 Da.
Categories: Benzimidazoles Heterocyclic Compounds, Fused-Ring Piperidines
Cross-references: BindingDB: 50206160 CHEMBL245621 PDB: MJV ZINC: ZINC000000537818
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P14416 DRD2 Homo sapiens Human PF00001 8.2 IC50 ChEMBL;BindingDB
Q13393 PLD1 Homo sapiens Human PF00169 PF00614 PF13091 PF00787 7.7 IC50 ChEMBL;BindingDB
O14939 PLD2 Homo sapiens Human PF00614 PF13091 PF00787 6.5 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q13393 PLD1 Phospholipase D1 inhibitor targets