Molecule Details
InChIKeyNBGYLHIDCLVBHE-UHFFFAOYSA-N
Compound Name3,13-Diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
Canonical SMILESO=C1NCc2c1c1c(c3[nH]c4ccccc4c23)Cc2ccccc2-1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.95
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16584 MAP3K11 Homo sapiens Human PF07714 PF14604 7.4 IC50 ChEMBL;BindingDB
P80192 MAP3K9 Homo sapiens Human PF07714 PF14604 7.2 IC50 ChEMBL;BindingDB
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 7.0 pIC50 TTD_MultiTarget
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.0 IC50 ChEMBL;BindingDB
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.8 IC50 ChEMBL
Q02779 MAP3K10 Homo sapiens Human PF07714 PF14604 6.4 IC50 ChEMBL;BindingDB