Molecule Details
InChIKeyNAXSRXHZFIBFMI-UHFFFAOYSA-N
Canonical SMILESO=C(O)Cc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.46
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB03791
Drug NameGW-3965
CAS Number405911-09-3
Groups experimental
ATC Codes nan
DescriptionGW-3965 is a liver X receptor ligand.

Categories: Acids, Carbocyclic Amines Benzene Derivatives Benzyl Compounds Ligands
Cross-references: BindingDB: 19992 ChEBI: 79995 CHEMBL59030 ChemSpider: 394865 C15631 PDB: 965 PubChem:447905 PubChem:46507779 ZINC: ZINC000003966253
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P55055 NR1H2 Homo sapiens Human PF00104 PF00105 7.9 IC50 ChEMBL;BindingDB
Q13133 NR1H3 Homo sapiens Human PF00104 PF00105 7.0 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P55055 NR1H2 Oxysterols receptor LXR-beta inhibitor targets
Q13133 NR1H3 Oxysterols receptor LXR-alpha inhibitor targets