Molecule Details
InChIKeyMZIOLOXGGOLJMJ-UHFFFAOYSA-N
Compound Name1-(Cyclopropylmethyl)-6-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]benzimidazol-2-amine
Canonical SMILESNc1nc2ccc(-c3c(-c4ccc(F)cc4)nc4sccn34)cc2n1CC1CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.69
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.9 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.7 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.1 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.5 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P04626 ERBB2 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.0 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL