N-[5-[[3,4-dimethyl-5-(4-prop-2-enoyl-1,4-diazepane-1-carbonyl)phenyl]methylsulfanyl]-1,3-thiazol-2-yl]cyclopropanecarboxamide

InChIKey	`MZEUUPBYZLOHJY-UHFFFAOYSA-N`
Compound Name	N-[5-[[3,4-dimethyl-5-(4-prop-2-enoyl-1,4-diazepane-1-carbonyl)phenyl]methylsulfanyl]-1,3-thiazol-2-yl]cyclopropanecarboxamide
Canonical SMILES	`C=CC(=O)N1CCCN(C(=O)c2cc(CSc3cnc(NC(=O)C4CC4)s3)cc(C)c2C)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.26
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P42681	TXK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.3	IC50	ChEMBL
P52333	JAK3	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.3	IC50	ChEMBL
Q08881	ITK	Homo sapiens	Human	PF00779 PF00169 PF07714 PF00017 PF00018	6.3	IC50	ChEMBL