InChIKey	MYSWGUAQZAJSOK-UHFFFAOYSA-N
Compound Name	Ciprofloxacin
Canonical SMILES	O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	6.35
Source	BindingDB;ChEMBL

DrugBank ID	DB00537
Drug Name	Ciprofloxacin
CAS Number	85721-33-1
Groups	approved investigational
ATC Codes	J01RA11 S03AA07 J01MA02 S02AA15 J01RA10 J01RA12 S01AE03
Description	Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.[A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The firs...

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Categories: 4-Quinolones Agents Causing Muscle Toxicity Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Chemically-Induced Disorders Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strong) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (moderate) Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (moderate) Cytochrome P-450 Enzyme Inhibitors Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Enzyme Inhibitors Fluoroquinolone Antibacterial Fluoroquinolones Heterocyclic Compounds, Fused-Ring MATE 1 Inhibitors MATE 1 Substrates MATE 2 Inhibitors MATE inhibitors MATE substrates Moderate Risk QTc-Prolonging Agents Ophthalmological and Otological Preparations Ophthalmologicals Otologicals P-glycoprotein substrates Photosensitizing Agents QTc Prolonging Agents Quinolines Quinolone Antimicrobial Quinolones Sensory Organs Topoisomerase II Inhibitors Topoisomerase Inhibitors

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Cross-references: BindingDB: 21690 ChEBI: 192484 CHEMBL8 ChemSpider: 2662 Drugs Product Database (DPD): 93 C05349 D00186 PDB: CPF PharmGKB: PA449009 PubChem:2764 PubChem:46504733 RxCUI: 2551 Therapeutic Targets Database: DAP001360 Wikipedia: Ciprofloxacin ZINC: ZINC000000020220