3,5-Dimethyl-4-[2-[[1-(3-methylsulfonylphenyl)-4-piperidyl]amino]pyrimidin-4-yl]oxy-benzonitrile

InChIKey	`MYCUZCCPKYVWHO-UHFFFAOYSA-N`
Compound Name	3,5-Dimethyl-4-[2-[[1-(3-methylsulfonylphenyl)-4-piperidyl]amino]pyrimidin-4-yl]oxy-benzonitrile
Canonical SMILES	`Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(c3cccc(S(C)(=O)=O)c3)CC2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.62
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9WKE8	reverse transcriptase	Human immunodeficiency virus type 1	Pathogen	PF00078	8.0	IC50	BindingDB
Q72547	pol	Human immunodeficiency virus type 1	Pathogen	PF00075 PF00078 PF06815 PF06817	7.3	IC50	ChEMBL