2-hydroxyethyl 2-[[3-[[2-methyl-1-oxo-1-[[4-(trifluoromethyl)-6H-pyrazolo[3,4-g][1,3]benzothiazol-2-yl]amino]propan-2-yl]amino]benzoyl]amino]acetate

InChIKey	`MXKWVQJXDBWLPO-UHFFFAOYSA-N`
Compound Name	2-hydroxyethyl 2-[[3-[[2-methyl-1-oxo-1-[[4-(trifluoromethyl)-6H-pyrazolo[3,4-g][1,3]benzothiazol-2-yl]amino]propan-2-yl]amino]benzoyl]amino]acetate
Canonical SMILES	`CC(C)(Nc1cccc(C(=O)NCC(=O)OCCO)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	6.71
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14965	AURKA	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL
Q00526	CDK3	Homo sapiens	Human	PF00069	7.1	IC50	ChEMBL
P24864	CCNE1	Homo sapiens	Human	PF02984 PF00134	6.8	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.6	IC50	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL
P14635	CCNB1	Homo sapiens	Human	PF02984 PF00134	6.3	IC50	ChEMBL