Molecule Details
| InChIKey | MWSVLDOKXAVVNZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(azetidin-1-ylsulfonyl)-4-[(8-benzhydryl-8-azabicyclo[3.2.1]octan-3-yl)methoxy]-5-cyclopropyl-2-fluorobenzamide |
| Canonical SMILES | O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC2CC3CCC(C2)N3C(c2ccccc2)c2ccccc2)cc1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.01 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35498 | SCN1A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 8.4 | IC50 | BindingDB |
| Q15858 | SCN9A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 8.3 | IC50 | ChEMBL;BindingDB |
| Q14524 | SCN5A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 7.4 | IC50 | BindingDB |