Molecule Details
| InChIKey | MVQIWKVEEIZQLL-WWGRRREGSA-N |
|---|---|
| Compound Name | 3-[(1S,2R)-2-(2-methoxyethyl)cyclopropyl]-5-[[(3R)-pyrrolidin-3-yl]methoxy]pyridine |
| Canonical SMILES | COCC[C@H]1C[C@@H]1c1cncc(OC[C@@H]2CCNC2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.13 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 8.3 | IC50 | ChEMBL;BindingDB |
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | IC50 | ChEMBL |
| Q05901 | CHRNB3 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | IC50 | ChEMBL |
| Q15825 | CHRNA6 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | IC50 | ChEMBL |