Molecule Details
| InChIKey | MTAOOMYAOJQXKB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-(6-Fluoro-3-pyridinyl)-6-methoxy-3,4-dimethyl-8-pyridin-3-ylimidazo[1,5-a]quinoxaline |
| Canonical SMILES | COc1cc(-c2cccnc2)cc2c1nc(C)c1c(C)nc(-c3ccc(F)nc3)n12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.3 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y233 | PDE10A | Homo sapiens | Human | PF01590 PF00233 | 9.1 | IC50 | ChEMBL |
| O00408 | PDE2A | Homo sapiens | Human | PF01590 PF00233 | 7.1 | IC50 | ChEMBL |
| O76074 | PDE5A | Homo sapiens | Human | PF01590 PF00233 | 6.6 | IC50 | ChEMBL |
| Q9HCR9 | PDE11A | Homo sapiens | Human | PF01590 PF00233 | 6.4 | IC50 | ChEMBL |