N-{4-[1-(2,3-Dihydroxypropyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea

InChIKey	`MRVCHPICZWIIEF-UHFFFAOYSA-N`
Compound Name	N-{4-[1-(2,3-Dihydroxypropyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl]phenyl}-N'-phenylurea
Canonical SMILES	`O=C(Nc1ccccc1)Nc1ccc(-c2nn(CC(O)CO)cc2-c2ccnc3[nH]ccc23)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.28
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q96GD4	AURKB	Homo sapiens	Human	PF00069	9.0	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.4	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	6.4	pIC50	TTD_MultiTarget