Molecule Details
| InChIKey | MRLLZKOSLONRSI-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[[[7-Cyano-4-[4-(trifluoromethoxy)phenyl]-1,3-benzothiazol-6-yl]amino]methyl]prop-2-enehydroxamic acid |
| Canonical SMILES | C=C(CNc1cc(-c2ccc(OC(F)(F)F)cc2)c2ncsc2c1C#N)C(=O)NO |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.16 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15562 | TEAD2 | Homo sapiens | Human | PF01285 PF17725 | 8.0 | IC50 | BindingDB |
| Q15561 | TEAD4 | Homo sapiens | Human | PF01285 PF17725 | 7.4 | IC50 | BindingDB |
| P28347 | TEAD1 | Homo sapiens | Human | PF01285 PF17725 | 7.1 | IC50 | BindingDB |
| P46937 | YAP1 | Homo sapiens | Human | PF15238 PF00397 | 7.1 | IC50 | BindingDB |
| Q99594 | TEAD3 | Homo sapiens | Human | PF01285 PF17725 | 6.2 | IC50 | BindingDB |