Molecule Details
InChIKeyMRFOPLWJZULAQD-SWGQDTFXSA-N
Canonical SMILESNc1ccc(/C=C/C(=O)NCc2cc3cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)cc4)cc(-c4ccc(F)cc4)c3o2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL6.96
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB19243
Drug NamePadnarsertib
CAS Number1643913-93-2
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Acids, Acyclic Acrylates Amides Amines Pyridines
Cross-references: CHEMBL4297467 ChemSpider: 38772371 PDB: 96Q ZINC: ZINC000253387914
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O96013 PAK4 Homo sapiens Human PF00786 PF00069 7.0 IC50 ChEMBL
P43490 NAMPT Homo sapiens Human PF18127 PF04095 6.9 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
O96013 PAK4 Serine/threonine-protein kinase PAK 4 inhibitor targets