(4-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-2-methoxyphenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone

InChIKey	`MRDGEZUUEBHTNO-UHFFFAOYSA-N`
Compound Name	(4-(4-(Benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)-2-methoxyphenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
Canonical SMILES	`COc1cc(Nc2nccc(-c3cc4ccccc4s3)n2)ccc1C(=O)N1CCC(N2CCCC2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.04
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O14920	IKBKB	Homo sapiens	Human	PF18397 PF12179 PF00069	7.3	IC50	ChEMBL;BindingDB
O15111	CHUK	Homo sapiens	Human	PF18397 PF12179 PF00069	7.0	IC50	ChEMBL;BindingDB
Q9Y6K9	IKBKG	Homo sapiens	Human	PF16516 PF11577 PF18414	6.8	IC50	ChEMBL