InChIKey	MQTOSJVFKKJCRP-BICOPXKESA-N
Compound Name	Azithromycin
Canonical SMILES	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	6.52
Source	ChEMBL

DrugBank ID	DB00207
Drug Name	Azithromycin
CAS Number	83905-01-5
Groups	approved investigational
ATC Codes	J01RA07 S01AA26 J01FA10 J01RA16
Description	Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175]. It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead o...

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Categories: Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates (strength unknown) Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Experimental Unapproved Treatments for COVID-19 Lactones Macrolide Antimicrobial Macrolides Macrolides, Lincosamides and Streptogramins Moderate Risk QTc-Prolonging Agents Ophthalmologicals P-glycoprotein inhibitors P-glycoprotein substrates Photosensitizing Agents Polyketides QTc Prolonging Agents

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Cross-references: BindingDB: 50373918 ChEBI: 2955 CHEMBL529 ChemSpider: 10482163 Drugs Product Database (DPD): 424 C06838 PDB: ZIT PharmGKB: PA448519 PubChem:447043 PubChem:46507743 RxCUI: 1299904 Therapeutic Targets Database: DNC001539 Wikipedia: Azithromycin ZINC: ZINC000085537026